What is progress? On what ethical and moral basis does man undertake the evolutionary path that determines his being in the world, his relationship with the environment and with his fellow men? On what foundations and through what purposes does man undertake his scientific research? What are the outcomes and testimonies that have contributed to a qualitative improvement in human life? What are the outcomes and testimonies of the errors committed, and that man continues to commit? Although in a continuous re-evaluation and alteration of behavioral orientation, and in response to his own needs and necessities, man creates that linear evolutionary path that leaves traces of himself and from which it is possible to detect the most intrinsic nature of him. This call asks these and further questions. These are open questions to which authors engaged in the various digital media respond by addressing the issue in various humanistic and scientific areas.